| Health / Medical Topics |
Amphotericin B Deoxycholate
The deoxycholate salt of amphotericin B, a polyene antifungal antibiotic produced by Streptomyces nodosus, with antifungal activity. Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane. This results in depolarization of the cell membrane, alterations in cell membrane permeability, leakage of important intracellular components, and cell rupture. This agent may also induce oxidative damage in fungal cells and has been reported to stimulate host immune cells. (NCI Thesaurus)
YOU MAY ALSO LIKE
A drug used in the treatment of infections caused by fungi. It is a type of antifungal.
Amphiregulin is a heparin-binding, heparin-inhibited member of the epidermal growth factor family and an autocrine growth factor for human keratinocytes. It seems…
Amphiphysin (695 aa, ~76 kDa) is encoded by the human AMPH gene. This protein may be involved in both exocytosis and cytoskeletal…
The amphipathic helix motif is characterized by a repeating pattern of polar (P) and non-polar (N) side-chains that can be summarized as…
A taxonomic class of vertebrates that include frogs, toads, newts, salamanders, and gymnophiona. Amphibians are cold blooded land animals that lay eggs…
A form of articulation in which the bones are connected by intervening substance admitting slight motion.
