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ANAPHYLAXIS
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I. (noun)
Sense 1
Meaning:
Hypersensitivity reaction to the ingestion or injection of a substance (a protein or drug) resulting from prior contact with a substance
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("anaphylaxis" is a kind of...):
hypersensitivity reaction (an inappropriate and excessive reaction to an allergen (as pollen or dust or animal hair or certain foods); severity ranges from mild allergy to severe systemic reactions leading to anaphylactic shock)
Domain category:
drug (a substance that is used as a medicine or narcotic)
Hyponyms (each of the following is a kind of "anaphylaxis"):
anaphylactic shock (a severe and rapid and sometimes fatal hypersensitivity reaction to a substance (especially a vaccine or penicillin or shellfish or insect venom) to which the organism has become sensitized by previous exposure)
Derivation:
anaphylactic (related to the hypersensitivity known as anaphylaxis)
Context examples:
Platelet Activating Factor Stabilization inhibits conjugation, transport, oxidation, or proteolysis of a phospholipid derivative (platelet activating factor) formed by platelets, basophils, neutrophils, monocytes, and macrophages that acts as a potent agent of platelet aggregation, inflammation, neutrophil activity, prostaglandin synthesis, and systemic anaphylaxis: hypotension, thrombocytopenia, neutropenia, and bronchoconstriction.
(Platelet Activating Factor Stabilization, NCI Thesaurus)
Platelet Activating Factor Degradation consists of conjugation, transport, and/or oxidation of a phospholipid derivative (platelet activating factor) formed by platelets, basophils, neutrophils, monocytes, and macrophages that acts as a potent agent of platelet aggregation, inflammation, neutrophil activity, prostaglandin synthesis, and systemic anaphylaxis: hypotension, thrombocytopenia, neutropenia, and bronchoconstriction.
(Platelet Activating Factor Degradation, NCI Thesaurus)
Resembling anaphylaxis.
(Anaphylactoid, NCI Thesaurus)
After implementing diets free of red meat, none of them experienced anaphylaxis in the 18 months to 3 years during which they were followed.
(NIAID scientists link cases of unexplained anaphylaxis to red meat allergy, National Institutes of Health)
Allergies and anaphylaxis are linked to the production of high levels of high-affinity IgE antibodies, which bind strongly to allergens to spur allergic reactions.
(Scientists discover immune cell subtype in mice that drives allergic reactions, National Institutes of Health)
Some episodes may even begin overnight when a person is sleeping, which is a particularly uncommon presentation for anaphylaxis.
(NIAID scientists link cases of unexplained anaphylaxis to red meat allergy, National Institutes of Health)
Scientists have identified a subtype of immune cell that drives the production of antibodies (link is external) associated with anaphylaxis and other allergic reactions.
(Scientists discover immune cell subtype in mice that drives allergic reactions, National Institutes of Health)
Six of the 70 study participants evaluated for unexplained frequent anaphylaxis tested positive for an allergy to galactose-α-1,3-galactose, or alpha-gal, a sugar molecule found in beef, pork, lamb and other red meats.
(NIAID scientists link cases of unexplained anaphylaxis to red meat allergy, National Institutes of Health)
They then took mice with normal immune systems and sensitized them with respiratory and food allergens to induce severe allergic reactions leading to anaphylaxis.
(Scientists discover immune cell subtype in mice that drives allergic reactions, National Institutes of Health)
Researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, found that some patients’ seemingly inexplicable anaphylaxis was actually caused by an uncommon allergy to a molecule found naturally in red meat.
(NIAID scientists link cases of unexplained anaphylaxis to red meat allergy, National Institutes of Health)
