Health / Medical Topics |
Androgen Receptor
Pronunciation
Androgen receptor (919 aa, ~99 kDa) is encoded by the human AR gene. This protein plays a role in the modulation of steroid-dependent gene transcription. (NCI Thesaurus)
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Androgen Metabolism consists of diverse biochemical reactions in the adrenal cortex that produce 19-carbon steroid hormones, which promote male sexual development or…
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A disorder of sexual development in persons with 46XY karyotype, characterized by an abnormality of the genes encoding androgen receptors. It results…
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Excessive secretion of androgens from the adrenal glands or gonads. Clinical manifestations may include virilization.
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Treatment to suppress or block the production or action of male hormones. This is done by having the testicles removed, by taking…
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An orally available, vitamin E derivative and androgen receptor (AR) antagonist with potential anti-oxidant, chemopreventative and antineoplastic activity. APC-100 binds to ARs…
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Androgen Activity Inhibition involves interference with, such as receptor binding, or restraint of the biological function of biochemical substances (androgens) secreted by…
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