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ANTI-TNF COMPOUND
I. (noun)
Sense 1
Meaning:
A class of drugs that block the action of tumor necrosis factor (TNF); used in cases of rheumatoid arthritis because TNF instigates inflammation of the joints
Classified under:
Nouns denoting man-made objects
Hypernyms ("anti-TNF compound" is a kind of...):
drug (a substance that is used as a medicine or narcotic)
Hyponyms (each of the following is a kind of "anti-TNF compound"):
Enbrel; etanercept (a genetically engineered anti-TNF compound (trade name Enbrel) consisting of receptors that bind TNF; it is injected twice a week in the treatment of rheumatoid arthritis)
infliximab; Remicade (an anti-TNF compound (trade name Remicade) consisting of an antibody directed against TNF; it is given intravenously at one-month to three-month intervals; used in treatment of regional enteritis and rheumatoid arthritis)
Arava; leflunomide (an anti-TNF compound (trade name Arava) that is given orally; can slow the progression of rheumatoid arthritis by slowing the proliferation of white blood cells which reduces inflammation in the synovium)