| Library / English Dictionary |
ANTIMETABOLITE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
An antineoplastic drug that inhibits the utilization of a metabolite
Classified under:
Nouns denoting man-made objects
Hypernyms ("antimetabolite" is a kind of...):
antineoplastic; antineoplastic drug; cancer drug (any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function)
Hyponyms (each of the following is a kind of "antimetabolite"):
fluorouracil (an antimetabolite used to treat certain cancers)
mercaptopurine; Purinethol (a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia)
amethopterin; methotrexate; methotrexate sodium (toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis)
Context examples:
An antimetabolite with an unknown or unspecified mechanism of action.
(Miscellaneous Antimetabolite, NCI Thesaurus)
An arabinonucleoside antimetabolite with antineoplastic activity.
(Nelarabine, NCI Thesaurus)
An oral formulation of the phosphate salt of fludarabine, a synthetic purine nucleoside analogue antimetabolite with antineoplastic activity.
(Oral Fludarabine Phosphate, NCI Thesaurus)
An injectable collagen matrix gel containing the antimetabolite methotrexate and the sympathicomimetic agent epinephrine with potential antineoplastic activity.
(Methotrexate-E Therapeutic Implant, NCI Thesaurus)
The sodium salt of methotrexate, an antimetabolite with antineoplastic and immunomodulating properties.
(Methotrexate Sodium, NCI Thesaurus)
The anhydrous form of mercaptopurine, a thiopurine-derivative antimetabolite with antineoplastic and immunosuppressive activities.
(Mercaptopurine Anhydrous, NCI Thesaurus)
An oral suspension containing the thiopurine-derivative antimetabolite 6-mercaptopurine, with potential antineoplastic activity.
(Mercaptopurine Oral Suspension, NCI Thesaurus)
An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities.
(Methotrexate, NCI Thesaurus)
A dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine, with potential antineoplastic activity.
(DNA Methyltransferase Inhibitor SGI-110, NCI Thesaurus)
An antimetabolite and folate analogue with anti-proliferative activity.
(Dideaza-5,6,7,8-Tetrahydrofolic Acid, NCI Thesaurus)
