Health / Medical Topics |
Apolizumab
Pronunciation
Definition 1
A substance being studied in the treatment of hematologic (blood) cancers. Apolizumab binds to a protein called ID10, which is found on the surface of some types of immune cells and cancer cells. It may help the immune system kill cancer cells. It is a type of monoclonal antibody. (NCI Dictionary)
Definition 2
A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro. (NCI Thesaurus)
YOU MAY ALSO LIKE
The determination of the ratio of the apolipoprotein J compared to creatinine present in a sample. The measurement may be expressed as…
The determination of the amount of apolipoprotein J present in a sample.
The determination of the amount of apolipoprotein H present in a sample.
The determination of the amount of apolipoprotein E4 present in a sample.
Apolipoprotein E4 (317 aa, ~36 kDa) is encoded by the human APOE gene. This protein is involved in triglyceride metabolism.
The determination of the amount of apolipoprotein E present in a sample.