Armadillo Repeat

Identified in over 240 functionally diverse proteins from yeast to man, ARM Repeats are approximately 40-amino acids long and composed of two longer anti-parallel helices (H2 and H3) that follow a perpendicular short helix (H1). Tandem repeats form a right-handed superhelix (3 helixes per unit); tight repeat packing creates a cylindrical hydrophobic core throughout the structure. Lined by highly conserved residues, the positively charged groove of the superhelix appears to mediate interaction with acidic surfaces of target proteins. Despite amino acid variability, ARM repeat structures are highly conserved. Though involved in protein-protein interactions, no common features among target proteins have been identified. ARM repeats have a common phylogenetic origin with the HEAT repeat; both contain seven highly conserved hydrophobic residues. (NCI Thesaurus)

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Armadillo

Any of several small, burrowing, chiefly nocturnal mammals with body covered with strong horny plates.

Arm Type Code

A coded value specifying the kind of arm.

Arm Target Accrual Number Range

A range of integers specifying the minimum and maximum number of subjects to be accrued for the arm.

Arm Skin

The skin or integument covering the arm.

Arm Recoil Result

The result obtained from a test commonly administered to assess the physiologic response to extending the arms as straight as possible alongside…

Arm Recoil

A test commonly administered to assess the physiologic response to extending the arms as straight as possible alongside the body when lying…