Health / Medical Topics

    Base Pair Miscoding

    Any DNA sequence rearrangement that results in the exchange of the original sequence with noncomplementary bases, resulting in a mismatched DNA duplex. Such events occur as a result of low-fidelity repair or replication reactions. If left unrepaired, base pair miscoding can result in mutation to one of the daughter DNA duplexes. (NCI Thesaurus)




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