BCL2

A protein that helps control whether a cell lives or dies by blocking a type of cell death called apoptosis. The gene for BCL2 is found on chromosome 18, and transfer of the BCL2 gene to a different chromosome is seen in many B-cell leukemias and lymphomas. This causes the BCL2 protein to be made in larger amounts, which may keep cancer cells from dying. Also called B-cell leukemia/lymphoma 2 protein. (NCI Dictionary)

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Human BCL11B wild-type allele is located in the vicinity of 14q32.2 and is approximately 102 kb in length. This allele, which encodes…

BCL11B Gene

This gene may play a role in tumor suppression, signaling and T cell development.

BCL11A wt Allele

Human BCL11A wild-type allele is located in the vicinity of 2p16.1 and is approximately 102 kb in length. This allele, which encodes…

BCL11A Gene

This gene is involved in both the modulation of cell shape and lymphopoiesis.

BCL10 wt Allele

Human BCL10 wild-type allele is located in the vicinity of 1p22 and is approximately 12 kb in length. This allele, which encodes…

BCL10 Gene

This gene is involved in the promotion of apoptosis.