BCL6/LCP1 Fusion Gene

A fusion gene that results from a chromosomal translocation t(3;13)(q27;q14) which fuses the promoter region of the BCL6 gene near the 5' end of the LCP1 gene. This rearrangement is associated with aberrant expression of the LCP1 gene product and non-Hodgkin follicular lymphoma and Burkitt lymphoma. (NCI Thesaurus)

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BCL6 wt Allele

Human BCL6 wild-type allele is located in the vicinity of 3q27 and is approximately 24 kb in length. This allele, which encodes…

BCL6 Protein

BCL6 protein is may be a transcription factor and contains six zinc finger motifs and shares an N-terminal POZ domain homologous to…

BCL6 Gene

This gene is involved in transcriptional repression and plays a role in the modulation of B-cell responses.

BCL3 wt Allele

Human BCL3 wild-type allele is located within 19q13.1-q13.2 and is approximately 11 kb in length. This allele, which encodes B-cell lymphoma 3-encoded…

BCL3 Gene

This gene is involved in transcriptional co-activation and signal transduction.

BCL2L2 wt Allele

Human BCL2L2 wild-type allele is located within 14q11.2-q12 and is approximately 5kb in length. This allele, which encodes apoptosis regulator Bcl-W protein,…