BCL7A Protein

Encoded by widely expressed human BCL7A Gene, 231-aa 25-kD serine-rich BCL7A Protein has 90% sequence identity (N-terminal 51-aa) with BCL7B and BCL7C; possible members of an evolutionarily conserved family. BCL7A exhibits no recognizable motifs but shows homology with actin-binding Caldesmon. Recurrent three-way translocations of BCL7A with MYC and IGH occur in a high-grade B cell non-Hodgkin (Burkitt) lymphoma; the N-terminal BCL7A region is disrupted. (NCI Thesaurus)

YOU MAY ALSO LIKE

BCL7A Gene

This gene may play a role in signal transduction.

BCL6/LCP1 Fusion Gene

A fusion gene that results from a chromosomal translocation t(3;13)(q27;q14) which fuses the promoter region of the BCL6 gene near the 5'…

BCL6 wt Allele

Human BCL6 wild-type allele is located in the vicinity of 3q27 and is approximately 24 kb in length. This allele, which encodes…

BCL6 Protein

BCL6 protein is may be a transcription factor and contains six zinc finger motifs and shares an N-terminal POZ domain homologous to…

BCL6 Gene

This gene is involved in transcriptional repression and plays a role in the modulation of B-cell responses.

BCL3 wt Allele

Human BCL3 wild-type allele is located within 19q13.1-q13.2 and is approximately 11 kb in length. This allele, which encodes B-cell lymphoma 3-encoded…