Health / Medical Topics |
BCL7A wt Allele
Human BCL7A wild-type allele is located in the vicinity of 12q24.13 and is approximately 40 kb in length. This allele encodes B-cell CLL/lymphoma 7 family member A protein. Expression of the allele is altered in non-Hodgkin lymphoma patients by a three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with the MYC gene and the immunoglobulin H locus. (NCI Thesaurus)
YOU MAY ALSO LIKE
Encoded by widely expressed human BCL7A Gene, 231-aa 25-kD serine-rich BCL7A Protein has 90% sequence identity (N-terminal 51-aa) with BCL7B and BCL7C;…
This gene may play a role in signal transduction.
A fusion gene that results from a chromosomal translocation t(3;13)(q27;q14) which fuses the promoter region of the BCL6 gene near the 5'…
Human BCL6 wild-type allele is located in the vicinity of 3q27 and is approximately 24 kb in length. This allele, which encodes…
BCL6 protein is may be a transcription factor and contains six zinc finger motifs and shares an N-terminal POZ domain homologous to…
This gene is involved in transcriptional repression and plays a role in the modulation of B-cell responses.