| Health / Medical Topics |
Becatecarin
A synthetic diethylaminoethyl analogue of the indolocarbazole glycoside antineoplastic antibiotic rebeccamycin. Becatecarin intercalates into DNA and stabilizes the DNA-topoisomerase I complex, thereby interfering with the topoisomerase I-catalyzed DNA breakage-reunion reaction and initiating DNA cleavage and apoptosis. (NCI Thesaurus)
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The number of heartbeats measured per minute time.
The number of a specific beat.
A point of contact between moving parts designed for support or to reduce friction.
