| Health / Medical Topics |
Belimumab
A fully human IgG1 monoclonal antibody directed against B-Lymphocyte stimulator protein (BlyS or TNFSF13B) with potential immunomodulating activity. Belimumab specifically recognizes and inhibits the biological activity of BlyS, thereby preventing the binding of BlyS to B-lymphocytes. This inhibits the maturation of B-lymphocytes and may induce apoptosis in B-lymphocytes. In addition, it may decrease B-lymphocyte proliferation and/or survival. BlyS, a member of TNF family supporting B-lymphocyte maturation and survival, has been implicated in the pathogenesis of autoimmune diseases and B-lymphocyte malignancies. (NCI Thesaurus)
YOU MAY ALSO LIKE
Faith based on a series of beliefs but not formalized into a religion; also, a fixed coherent set of beliefs prevalent in…
The Belgian Tervuren is a slender dog, squarely proportioned and solidly muscled, but not bulky. The erect ears are equilateral triangles. The…
The Belgian Sheepdog is a muscular black dog but not heavy. It has triangular, erect ears. It may be completely black, or…
The Belgian Malinois is a muscular dog but not heavy. It has short, erect ears and a short-haired coat that is fawn…
A drug used to treat peripheral T-cell lymphoma that has come back or has not gotten better with other treatment. It is…
A transforming growth factor beta2 (TGF-beta2) antisense gene-modified allogeneic tumor cell vaccine with potential immunostimulatory and antineoplastic activities. Belagenpumatucel-L is prepared by…
