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    Benign Giant Cell Tumor of Bone

    Definition 1

    A benign, locally aggressive bone tumor, usually arising in the end of long bones or the vertebrae. The tumor is composed of round or oval mononuclear cells and uniformly distributed osteoclast-like giant cells. Clinical presentation includes pain, edema, and decrease range of motion in the affected joint. (NCI Thesaurus)

    Definition 2

    A benign neoplasm of bone comprised of giant cells (osteoclast-like) and mononuclear cells. (NCI Thesaurus/CDISC)




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