| Library / English Dictionary |
BLOOD-BRAIN BARRIER
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A mechanism that creates a barrier between brain tissues and circulating blood; serves to protect the central nervous system
Example:
the brain was protected from the large molecules of the virus by the blood-brain barrier
Classified under:
Nouns denoting natural objects (not man-made)
Hypernyms ("blood-brain barrier" is a kind of...):
barrier (anything serving to maintain separation by obstructing vision or access)
Context examples:
They are lipophilic and can cross the blood-brain barrier.
(Nitrosourea Compound, NCI Thesaurus)
Conjugation with PEG prevents penetration through the blood-brain barrier (BBB) and into the central nervous system (CNS), and therefore does not interfere with the analgesic effect of opioids.
(Oral Pegylated Naloxol, NCI Thesaurus)
The CTZ is located in the area postrema on the dorsal surface of the medulla oblongata at the caudal end of the fourth ventricle and outside the blood-brain barrier (BBB).
(Palonosetron hydrochloride, NCI Thesaurus)
An anticancer drug that can cross the blood-brain barrier.
(Nitrosourea, NCI Dictionary)
In addition, JNJ-26483327 crosses the blood-brain barrier (BBB).
(Multitargeted Tyrosine Kinase Inhibitor JNJ-26483327, NCI Thesaurus)
Desglymidodrine diffuses poorly across the blood-brain barrier, and is therefore not associated with effects on the central nervous system (CNS).
(Midodrine, NCI Thesaurus)
Desglymidodrine diffuses poorly across the blood-brain barrier, and is therefore not associated with effects on the central nervous system.
(Midodrine Hydrochloride, NCI Thesaurus)
It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
(Moxalactam, NLM, Medical Subject Headings)
An alpha-2 adrenergic agonist that crosses the blood-brain barrier.
(Clonidine, NLM, Medical Subject Headings)
In addition, diazepinomicin is able to cross the blood-brain barrier, thereby reaching therapeutic concentrations in the brain.
(Diazepinomicin, NCI Thesaurus)
