| Health / Medical Topics |
Chemokine-Like Receptor 1
Chemokine-Like Receptor 1, encoded by the human CMKLR1 gene, is an orphan receptor that belongs to G Protein-Coupled Receptor. This protein may be a chemotactic peptide receptor. It is expressed during bone development and may have a function in bone metabolism. It is prominently expressed in developing osseous and cartilaginous tissue. It is also found in adult parathyroid glands. It also acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). Two isoforms (A, B) are produced by alternative splicing. (From Swiss-Prot and NCI) (NCI Thesaurus)
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