| Health / Medical Topics |
Chimeric Monoclonal Antibody B72.3
A synthetic chimeric molecule in which a mouse monoclonal antibody variable region directed against the tumor-associated glycoprotein 72 (TAG-72) is fused to a human antibody constant region. This agent reacts to most human adenocarcinomas (colorectal, gastric, pancreatic, ovarian, endometrial, mammary) but has weak or undetectable reactivity to most normal tissues. (NCI Thesaurus)
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