| Health / Medical Topics |
Chloride Anion Exchanger
Encoded by human SLC26A3 Gene (SLC26A/SulP Transporter Family), 764-aa 85-kDa Chloride Anion Exchanger is a sulfate/chloride/bicarbonate transmembrane glycoprotein exchange transporter containing 1 STAS domain and localized in lower intestinal columnar epithelial apical membranes and some goblet cells. Involved in absorbtion, SLC26A3 mediates electrolyte and fluid absorption. Defects in SLC26A3 are the cause of congenital chloride diarrhea (CLD). (NCI Thesaurus)
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