Health / Medical Topics |
Cholera Toxin
Secreted by Vibrio cholerae, Cholera Toxin is a natural bacterial enterotoxin consisting of major components heavy A- and light B peptides (choleragenoid) that initiates a signaling cascade in intestinal epithelial cells causing a dysfunction of chloride channels, loss of water, and diarrhea. B peptide anchors the protein to epithelia; A peptide enters the cytoplasm and activates adenylate cyclase. Due to its cytotoxicity, cholera toxin is being studied for tumor cell targeting and cancer chemotherapy. (NCI Thesaurus)
YOU MAY ALSO LIKE
![](/lib/px2x1.gif)
Cholera is a bacterial infection that causes diarrhea. The cholera bacterium is usually found in water or food contaminated by feces…
![](/lib/px2x1.gif)
Solid material that forms in the gallbladder or common bile duct. Choleliths are made of cholesterol or other substances found in the…
![](/lib/px2x1.gif)
Cystic dilatation of the hepatic duct or bile duct.
![](/lib/px2x1.gif)
The determination of the amount of cholecystokinin hormone present in a sample.
![](/lib/px2x1.gif)
An orally active, benzodiazepine type, selective cholecystokinin B receptor (CCKBR; CCK2R; gastrin receptor) antagonist with potential gastric acid reducing and antiproliferative…
![](/lib/px2x1.gif)
An acute or chronic inflammation of the gallbladder associated with the presence of gallstones.
![](/lib/px2x1.gif)