Clear cell sarcoma of soft tissue

Pronunciation

Definition 1

A soft tissue tumor that begins in a tendon (tough, fibrous, cord-like tissue that connects muscle to bone or to another structure). Clear cell sarcoma of soft tissue has certain markers that are also found on malignant melanoma (a type of skin cancer). It usually occurs in the leg or arm. Also called malignant melanoma of soft parts. (NCI Dictionary)

Definition 2

A rare malignant neoplasm with melanocytic differentiation characterized by the presence of polygonal or spindle shaped clear cells. This sarcoma usually affects the tendons and aponeuroses and is associated with a poor prognosis due to recurrences and metastases. (NCI Thesaurus)

Definition 3

A soft tissue tumor of young adults with melanocytic differentiation, typically involving tendons and aponeuroses. There is a recurrent cytogenetic aberration: t(12;22)(q13;q12). (NCI Thesaurus)

YOU MAY ALSO LIKE

Clear Cell Renal Cell Carcinoma

A malignant epithelial neoplasm of the kidney characterized by the presence of lipid-containing clear cells within a vascular network. The tumor…

Clear Cell Papillary Cystadenoma

A benign cystic glandular epithelial neoplasm characterized by the presence of neoplastic clear or hobnail cells which form papillary structures. There is…

Clear Cell Odontogenic Carcinoma

A usually aggressive malignant neoplasm arising from tooth-forming tissues. It more often affects older females and more frequently occurs in the…

Clear Cell Neoplasm

A purely morphologic term that describes a neoplasm in which all or the majority of the neoplastic cells have a clear cytoplasm,…

Clear Cell Myomelanocytic Tumor of the Falciform Ligament/Ligamentum Teres

A very rare, usually benign neoplasm with perivascular epithelioid cell differentiation characterized by the presence of clear spindle cells arranged in fascicles…

Clear Cell Meningioma

A WHO grade II morphologic variant of meningioma characterized by the presence of clear glycogen-rich polygonal cells.