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CONFORMATION
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I. (noun)
Sense 1
Meaning:
Acting according to certain accepted standards
Example:
their financial statements are in conformity with generally accepted accounting practices
Synonyms:
abidance; compliance; conformation; conformity
Classified under:
Nouns denoting acts or actions
Hypernyms ("conformation" is a kind of...):
cooperation (joint operation or action)
Hyponyms (each of the following is a kind of "conformation"):
formality (compliance with formal rules)
line (acting in conformity)
honoring; observance (conformity with law or custom or practice etc.)
keeping (conformity or harmony)
Derivation:
conform (be similar, be in line with)
Sense 2
Meaning:
Any spatial attributes (especially as defined by outline)
Example:
he could barely make out their shapes
Synonyms:
configuration; conformation; contour; form; shape
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("conformation" is a kind of...):
spatial property; spatiality (any property relating to or occupying space)
Attribute:
straight (having no deviations)
crooked (having or marked by bends or angles; not straight or aligned)
Hyponyms (each of the following is a kind of "conformation"):
stratification (a layered configuration)
crookedness (having or distinguished by crooks or curves or bends or angles)
straightness (freedom from crooks or curves or bends or angles)
roundness (the property possessed by a line or surface that is curved and not angular)
curvature; curve (the property possessed by the curving of a line or surface)
narrowing (an instance of becoming narrow)
angularity (the property possessed by a shape that has angles)
convexity; convexness (the property possessed by a convex shape)
concaveness; concavity (the property possessed by a concave shape)
lobularity (the property of having lobules)
topography (the configuration of a surface and the relations among its man-made and natural features)
bluntness; dullness (without sharpness or clearness of edge or point)
keenness; sharpness (thinness of edge or fineness of point)
Sense 3
Meaning:
A symmetrical arrangement of the parts of a thing
Classified under:
Nouns denoting two and three dimensional shapes
Hypernyms ("conformation" is a kind of...):
balance; counterbalance; equilibrium; equipoise (equality of distribution)
Context examples:
Ligand-bound NR conformation allows coactivator interaction with the hormone-binding domain that mediates interaction with heat shock proteins, cyclophilins, and hormone.
(Nuclear Receptor Gene, NCI Thesaurus)
This allele, which encodes merlin protein, plays a role in the mediation of protein localization, cytoskeletal conformation and ion transport.
(NF2 wt Allele, NCI Thesaurus)
Computer technique for predicting conformation of protein or other macromolecule by rotating all bonds so as to minimize free energy; in looser parlance, term may refer to intramolecular motion.
(Molecular Dynamics, NIH CRISP Thesaurus)
A class of fibrous proteins or scleroproteins important both as structural proteins and as keys to the study of protein conformation.
(Cytokeratin, NLM, Medical Subject Headings)
Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells.
(Eflornithine, NCI Thesaurus)
B-DNA is the most common DNA conformation in vivo and the favored conformation at high water concentrations.
(B-DNA, NCI Thesaurus)
Base mutations will often result in altered conformations, with altered mobilities, which can be visualized following separation in non-denaturing gels.
(Conformation Dependent Mutation Detection, NCI Thesaurus/OSP)
Anti-HER3 monoclonal antibody LJM716 possesses a novel mechanism of action; LJM716 binds to and locks HER3 in the inactive conformation and does not interfere with its interaction with neuregulin (NRG).
(Anti-HER3 Monoclonal Antibody LJM716, NCI Thesaurus)
Base pairs are tilted to helix axis and displaced from axis and sugar pucker is C3'-endo (in RNA 2'-OH inhibits C2'-endo conformation).
(A-DNA, NCI Thesaurus)
This allele, which encodes collagen alpha-5(IV) chain protein, plays a role in the modulation of the conformation of the extracellular matrix.
(COL4A5 wt Allele, NCI Thesaurus)
