CTCAE Grade 4 Oral Cavity Pulmonary Fistula

Life-threatening consequences; operative intervention with thoracoplasty, chronic open drainage or multiple thoracotomies indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Oral Cavity Pain

CTCAE Grade 4 Oral Cavity or Gum Infection with Unknown Absolute Neutrophil Count

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

CTCAE Grade 4 Oral Cavity or Gum Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

CTCAE Grade 4 Oral Cavity or Gum Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

CTCAE Grade 4 Oral Cavity NOS Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Oral Cavity Mucositis or Stomatitis by Functional or Symptomatic Classification

Symptoms associated with life-threatening consequences