CTCAE Grade 4 Psychosis Including Hallucinations and Delusions

Harmful to others or self; life-threatening consequences (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Proteinuria

CTCAE Grade 4 Prostate Stricture or Stenosis

Life-threatening consequences; organ failure or operative intervention requiring organ resection indicated

CTCAE Grade 4 Prostate Perforation

Life-threatening consequences or organ failure; operative intervention requiring organ resection indicated

CTCAE Grade 4 Prostate Pain

CTCAE Grade 4 Prostate Obstruction

Life-threatening consequences; organ failure or operative intervention requiring complete organ resection indicated

CTCAE Grade 4 Prostate Intra-Operative Injury

Life threatening consequences; disabling