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    CTCAE Grade 4 Retinopathy

    Blindness (20/200 or worse) (NCI Thesaurus/CTCAE)




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    CTCAE Grade 4 Retinoic Acid Syndrome
    Life-threatening; ventilatory support indicated
    CTCAE Grade 4 Retinal Detachment
    Blindness (20/200 or worse)
    CTCAE Grade 4 Retina Intra-Operative Injury
    Life threatening consequences; disabling
    CTCAE Grade 4 Restrictive Cardiomyopathy
    Refractory CHF, poorly controlled; intervention such as ventricular assist device, or heart transplant indicated
    CTCAE Grade 4 Respiratory Tract Hemorrhage NOS
    Life-threatening consequences; major urgent intervention indicated
    CTCAE Grade 4 Renal Failure
    Chronic dialysis or renal transplant indicated

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