Health / Medical Topics |
CTCAE Grade 4 Tumor Flare
Disabling (NCI Thesaurus/CTCAE)
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Life-threatening (e.g., arrhythmia associated with CHF, hypotension, syncope, shock)


Life-threatening airway compromise; tracheotomy or intubation indicated

Symptoms associated with life-threatening consequences

Tissue necrosis; significant spontaneous bleeding; life-threatening consequences
