CTCAE Grade 4 Urethra Fistula

Life-threatening consequences; operative intervention requiring partial or full organ resection; permanent urinary diversion (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Ureter Stricture or Stenosis

Life-threatening consequences; organ failure or operative intervention requiring organ resection indicated

CTCAE Grade 4 Ureter Perforation

Life-threatening consequences or organ failure; operative intervention requiring organ resection indicated

CTCAE Grade 4 Ureter Obstruction

Life-threatening consequences; organ failure or operative intervention requiring complete organ resection indicated

CTCAE Grade 4 Ureter Leak

CTCAE Grade 4 Ureter Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Ureter Infection with Unknown Absolute Neutrophil Count

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)