CTCAE Grade 4 Urethra Obstruction

Life-threatening consequences; organ failure or operative intervention requiring complete organ resection indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Urethra Leak

CTCAE Grade 4 Urethra Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Urethra Infection with Unknown Absolute Neutrophil Count

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

CTCAE Grade 4 Urethra Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

CTCAE Grade 4 Urethra Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

CTCAE Grade 4 Urethra Hemorrhage

Life-threatening consequences; major urgent intervention indicated