CTCAE Grade 4 Viral Hepatitis

Decompensated liver function (e.g., ascites, coagulopathy, encephalopathy, coma) (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Ventricular Tachycardia

Life-threatening (e.g., arrhythmia associated with CHF, hypotension, syncope, shock)

CTCAE Grade 4 Ventricular Flutter

Life-threatening (e.g., arrhythmia associated with CHF, hypotension, syncope, shock)

CTCAE Grade 4 Ventricular Fibrillation

Life-threatening (e.g., arrhythmia associated with CHF, hypotension, syncope, shock)

CTCAE Grade 4 Ventricular Arrhythmia NOS

Life-threatening (e.g., arrhythmia associated with CHF, hypotension, syncope, shock)

CTCAE Grade 4 Vein NOS Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Vein Infection with Unknown Absolute Neutrophil Count

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)