CTLA4 wt Allele

Human CTLA4 wild-type allele is located within 2q33 and is approximately 6 kb in length. This allele, which encodes cytotoxic T-lymphocyte protein 4, is involved in signal transduction and T-cell regulation. Variant alleles generated from mutations in the gene, have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. (NCI Thesaurus)

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This gene is involved in T-cell mediation and receptor signal transduction.

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CTHRC1 wt Allele

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CTGF wt Allele

Human CTGF wild-type allele is located in the vicinity of 6q23.1 and is approximately 3 kb in length. This allele, which encodes…