CYP17A1 wt Allele

Human CYP17A1 wild-type allele is located in the vicinity of 10q24.3 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 17A1 protein, plays a role in the synthesis of progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Functional mutations in the CYP17A1 gene typically result in 17-alpha-hydroxylase deficiency which, in turn, causes adrenal hyperplasia. (NCI Thesaurus)

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CYP17A1 Gene

This gene plays a role in the metabolism of estrogen and glucocorticoids. It is also involved in sexual maturation.

CYP17 Inhibitor CFG920

An orally available inhibitor of the steroid 17-alpha-hydroxylase/C17,20 lyase (CYP17A1 or CYP17), with potential antiandrogen and antineoplastic activities. Upon oral administration, CYP17…

CYP11B2 wt Allele

Human CYP11B2 wild-type allele is located within 8q21-q22 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 11B2,…

CYP11B2 Gene

This gene is involved in mineralocorticoid metabolism.

CYP11B1 wt Allele

Human CYP11B1 wild-type allele is located within 8q21 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 11B1,…

CYP11B1 Gene

This gene plays a role in the metabolism of glucucorticoids.