CYP27B1 wt Allele

Human CYP27B1 wild-type allele is located within 12q13.1-q13.3 and is approximately 5 kb in length. This allele, which encodes 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial protein, is involved in the biosynthesis of the active form of vitamin D3. Many allelic variants of the CYP27B1 gene encode proteins that are either inactive or exhibit reduced catalytic activity which, in turn, results in vitamin D-dependent rickets type I. (NCI Thesaurus)

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CYP27B1 Gene

This gene is involved in vitamin D metabolism and calcium homeostasis.

CYP27A1 wt Allele

Human CYP27A1 wild-type allele is located within 2q33-qter and is approximately 34 kb in length. This allele, which encodes sterol 26-hydroxylase, mitochondrial…

CYP27A1 Gene

This gene is involved in cholesterol homeostasis and bile synthesis.

CYP26B1 wt Allele

Human CYP26B1 wild-type allele is located in the vicinity of 2p13.2 and is approximately 19 kb in length. This allele, which encodes…

CYP26B1 Gene

This gene plays a role in the metabolism of retinoic acid.

CYP24A1 wt Allele

Human CYP24A1 wild-type allele is located within 20q13.2-q13.3 and is approximately 21 kb in length. This allele, which encodes 1,25-dihydroxyvitamin D(3) 24-hydroxylase,…