CYP2C19*10 Allele

Human CYP2C19*10 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19 wild-type allele, encodes cytochrome P450 2C19*10 protein. The CYP2C19*10 allele exhibits a clinically-relevant SNP (c.680C>T) in exon 5 that results in a P227L coding change. This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 2C19*10 protein. (NCI Thesaurus)

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Human CYP2C19*1 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19…

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Human CYP2C19 wild-type allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, which encodes cytochrome P450 2C19…

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This gene is involved in the metabolism of drugs and xenobiotics.

CYP2C18 wt Allele

Human CYP2C18 wild-type allele is located within 10q24 and is approximately 53 kb in length. This allele, which encodes cytochrome P450 2C18…

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This gene plays a role in the metabolism of fatty acids, tryptophan, drugs and xenobiotics.

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Human CYP2B6 wild-type allele is located in the vicinity of 19q13.2 and is approximately 27 kb in length. This allele, which encodes…