Health / Medical Topics |
CYP2C8*3 Allele
Human CYP2C8*3 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form of the CYP2C8 wild-type allele, encodes cytochrome P450 2C8*3 protein. The CYP2C8*3 allele exhibits clinically-relevant SNPs (c.416G>A, c.1196A>G) in exons 3 and 8 that result in coding changes (R139K, K399R). These alterations in protein sequence severely decrease the enzymatic activity of the cytochrome P450 2C8*3 protein. (NCI Thesaurus)
YOU MAY ALSO LIKE
Human CYP2C8*2 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form…
Human CYP2C8 wild-type allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, which encodes…
This gene plays a role in drug metabolism. It is also involved in the oxidation of both endobiotics and xenobiotics.
Human CYP2C19*9 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19…
Human CYP2C19*8 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19…
Human CYP2C19*7 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19…