Health / Medical Topics

    CYP2D6*40 Allele

    Human CYP2D6*40 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*40 protein. The CYP2D6*40 allele exhibits an 18 nucleotide insertion (g.1863insTTTCGCCCCTTTCGCCCC) that abolishes the enzymatic activity of the cytochrome P450 2D6*40 protein. (NCI Thesaurus)




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