Health / Medical Topics

    CYP2D6*7 Allele

    Human CYP2D6*7 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*7 protein. The CYP2D6*7 allele exhibits a clinically-relevant SNP (g.2935A>C) that results in a H324P coding change. This alteration in amino acid sequence causes an alteration of the 3D protein structure in close vicinity to the active site that abolishes the enzymatic activity of the cytochrome P450 2D6*7 protein. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    Human CYP2D6*6 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form…
    Human CYP2D6*5 allele is a variant form of the CYP2D6 wild-type allele. The CYP2D6*5 allele is a result of deletion of the…
    Human CYP2D6*44 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form…
    Human CYP2D6*42 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form…
    Human CYP2D6*41 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form…
    Human CYP2D6*40 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact