CYP3A4 wt Allele

Human CYP3A4 wild-type allele is located in the vicinity of 7q21.1 and is approximately 27 kb in length. This allele, which encodes cytochrome P450 3A4 protein, plays a role in the oxidation of steroids, drugs, carcinogens and other xenobiotics. CYP3A4 gene dysfunction is associated with both lung cancer and epipodophyllotoxin-induced leukemogenesis. (NCI Thesaurus)

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CYP3A4 Gene

This gene plays an role in the metabolism of numerous clinically-relevant drugs. It is also involved in the oxidation of both endogenous…

CYP3A Gene Locus

Human CYP3A gene locus is located within 7q21.3-q22.1 and is approximately 218 kb in length. This locus includes four protein-encoding genes, CYP3A4,…

CYP2E1*2 Allele

Human CYP2E1*2 allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, a variant form of the CYP2E1…

CYP2E1*1 Allele

Human CYP2E1*1 allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, a variant form of the CYP2E1…

CYP2E1 wt Allele

Human CYP2E1 wild-type allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, which encodes cytochrome P4502E1 protein,…

CYP2E1 Gene

This gene is involved in the metabolism of both endogenous and exogenous substrates.