Dysgerminoma

Pronunciation

Definition 1

A type of tumor that begins in the type of cells that give rise to egg cells and is most often found in the ovaries. Dysgerminomas may also occur in other places in the body, including the central nervous system. They are the most common type of ovarian germ cell tumor and can spread to other parts of the body. They are most common in females who are younger than 20 years old. (NCI Dictionary)

Definition 2

A malignant germ cell tumor characterized by the presence of a monotonous primitive germ cell population. The neoplastic cells form aggregates and have an abundant pale cytoplasm and uniform nuclei. The aggregates of the germ cells are separated by fibrous septa which contain inflammatory cells, mostly T-lymphocytes. It arises primarily in the ovaries, but can occur both primarily and secondarily at other sites, particularly the central nervous system. It responds to chemotherapy and radiotherapy. Its prognosis is related to the tumor stage. (NCI Thesaurus)

Definition 3

A malignant germ cell neoplasm characterized by the presence of a monotonous primitive germ cell population, primarily in the ovary. (NCI Thesaurus/CDISC)

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