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EBOLA VIRUS
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A filovirus that causes Ebola hemorrhagic fever; carried by animals; can be used as a bioweapon
Classified under:
Hypernyms ("Ebola virus" is a kind of...):
filovirus (animal viruses belonging to the family Filoviridae)
Holonyms ("Ebola virus" is a member of...):
Filoviridae (a family of threadlike RNA viruses that cause diseases in humans and nonhuman primates (monkeys and chimpanzees))
Context examples:
The researchers sequenced 99 Ebola virus genomes in total, as some people were sampled more than once.
(Genetics of the 2014 Ebola Outbreak, NIH)
Antibodies isolated from two survivors bound to an essential virus protein, called glycoprotein or GP, from Zaire, Bundibugyo and Sudan Ebola virus species, and prevented the viruses from entering host cells.
(Broadly acting antibodies found in plasma of Ebola survivors, National Institutes of Health)
The proteins are from Ebola virus (Kikwit strain), Sudan virus (Boniface strain, which also causes Ebola virus disease), Marburg virus (Angola strain) and Lassa virus (Josiah strain).
(Study vaccine protects monkeys against four types of hemorrhagic fever viruse, National Institutes of Health)
The researchers mined the human immune response to natural infection by the Ebola virus and found two antibodies, ADI-15878 and ADI-15742, which recognized the GP fusion loop — a section of a protein found on the surface of the Ebola virus.
(Antibodies from Ebola survivor protect mice and ferrets against related viruses, NIH)
2 of the mAbs (mAb110 and mAb114) had unique properties and were the most potent against Ebola virus.
(Experimental Ebola antibody protects monkeys, NIH)
The Ebola virus can cause severe illness and death in people and other primates.
(Genetics of the 2014 Ebola Outbreak, NIH)
Ebola virus uses GP to attach to cell membranes and initiate infection.
(Broadly acting antibodies found in plasma of Ebola survivors, National Institutes of Health)
A team of scientists of National Institute of Allergy and Infectious Diseases (NIAID) set out to develop a simplified treatment with fewer antibodies by generating mAbs from human survivors of Ebola virus disease.
(Experimental Ebola antibody protects monkeys, NIH)
Recent Ebola virus disease (EVD) outbreaks, including the 2013-2016 epidemic that ravaged West Africa and the 2018 outbreak in the Democratic Republic of the Congo, highlight the need for licensed treatments for this often-deadly disease.
(Broadly acting antibodies found in plasma of Ebola survivors, National Institutes of Health)
The untreated control macaque developed Ebola virus disease and succumbed to the virus, but the treated animals survived and remained free of Ebola symptoms.
(Experimental Ebola antibody protects monkeys, NIH)
