Efavirenz

Pronunciation

Definition 1

A drug used with other drugs to treat infection with the human immunodeficiency virus (HIV). It blocks HIV from making copies of itself. It is a type of non-nucleoside reverse transcriptase inhibitor and a type of antiviral agent. Also called Sustiva. (NCI Dictionary)

Definition 2

A synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity. Efavirenz binds directly to the human immunodeficiency virus type 1 (HIV-1) RT, an RNA-dependent DNA polymerase, blocking its function in viral DNA replication. In combination with other antiretroviral drugs, this agent has been shown to significantly reduce HIV viral load, retarding or preventing damage to the immune system and reducing the risk of developing AIDS. Efavirenz induces activity of the cytochrome P450 system, accelerating its own metabolism. (NCI Thesaurus)

YOU MAY ALSO LIKE

Efatutazone Dihydrochloride

The dihydrochloride salt of efatutazone, an orally bioavailable compound and an agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma) with potential antineoplastic…

Efatutazone

An orally bioavailable thiazolidinedione and an agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma) with potential antineoplastic activity. Efatutazone binds to and activates…

Efaproxiral Sodium

The sodium salt form of efaproxiral, a propanoic acid and allosteric modifier of hemoglobin, with radiosensitizing activity. Efaproxiral binds non-covalently to the…

Efaproxiral

A substance being studied in the treatment of brain tumors and some other types of cancer. It increases the amount of oxygen…

Efalizumab

A monoclonal antibody used to treat psoriasis (a chronic skin disease). It is also being studied in the treatment of graft-versus-host disease…

EF5

A drug that is used to plan cancer treatment by measuring oxygen levels in tumor cells.