Health / Medical Topics

    Erlotinib hydrochloride

    Pronunciation

    Definition 1

    A drug used to treat certain types of non-small cell lung cancer. It is also used with gemcitabine hydrochloride to treat pancreatic cancer that cannot be removed by surgery or has spread to other parts of the body. It is being studied in the treatment of other types of cancer. Erlotinib hydrochloride blocks a protein called epidermal growth factor receptor (EGFR), which may help keep cancer cells from growing. It is a type of EGFR tyrosine kinase inhibitor. Also called CP-358,774, OSI-774, and Tarceva. (NCI Dictionary)

    Definition 2

    The hydrochloride salt of a quinazoline derivative with antineoplastic properties. Competing with adenosine triphosphate, erlotinib reversibly binds to the intracellular catalytic domain of epidermal growth factor receptor (EGFR) tyrosine kinase, thereby reversibly inhibiting EGFR phosphorylation and blocking the signal transduction events and tumorigenic effects associated with EGFR activation. (NCI Thesaurus)

    Definition 3

    A drug used to treat certain types of non-small cell lung cancer. It is also used together with gemcitabine to treat pancreatic cancer and is being studied in the treatment of other types of cancer. Erlotinib hydrochloride is a type of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. (NCI Dictionary)




    YOU MAY ALSO LIKE

    A quinazoline derivative with antineoplastic properties. Competing with adenosine triphosphate, erlotinib reversibly binds to the intracellular catalytic domain of epidermal growth…
    The p44/42 MAP Kinase pathway consists of a protein kinase cascade linking growth and differentiation signals with transcription in the nucleus. Growth…
    An orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, MK-8353 inhibits both ERK phosphorylation and…
    An orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, GDC-0994 inhibits both ERK phosphorylation and…
    An orally available inhibitor of extracellular signal-regulated kinase (ERK) 1 and 2, with potential antineoplastic activity. Upon oral administration, BVD-523 inhibits both…
    A drug used to treat advanced basal cell carcinoma that has spread to other parts of the body or has come back…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact