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ESTROGEN
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I. (noun)
Sense 1
Meaning:
A general term for female steroid sex hormones that are secreted by the ovary and responsible for typical female sexual characteristics
Synonyms:
Classified under:
Hypernyms ("estrogen" is a kind of...):
sex hormone; steroid; steroid hormone (any hormone affecting the development and growth of sex organs)
Hyponyms (each of the following is a kind of "estrogen"):
DES; diethylstilbestrol; diethylstilboestrol; stilbestrol; stilboestrol (a potent estrogen used in medicine and in feed for livestock and poultry)
estradiol; oestradiol (the most powerful female hormone that occurs naturally; synthesized and used to treat estrogen deficiency and breast cancer)
estriol; oestriol (a naturally occurring estrogenic hormone; a synthetic form is used to treat estrogen deficiency)
estrone; Estronol; oestrone; theelin (a naturally occurring weak estrogenic hormone secreted by the mammalian ovary; synthesized (trade name Estronol) and used to treat estrogen deficiency)
hexestrol (estrogen compound used to treat menstrual irregularities and menopausal symptoms and to prevent pregnancy)
mestranol (a synthetic form of estrogen used in combination with a progestin in oral contraceptives)
Derivation:
estrogenic (relating to or caused by estrogen)
Context examples:
As such, estrogen receptor is a key regulator of proliferation and differentiation in mammary epithelia and represents a crucial prognostic indicator and therapeutic target in breast cancer.
(MTA3 Pathway, NCI Thesaurus/BIOCARTA)
It may block the effects of the hormone estrogen, which causes some breast cancer cells to grow, or block the blood flow to tumors.
(Naltrexone, NCI Dictionary)
Estrogens that are not steroids, but have a structural configuration resembling steroids and may mimic steroidal estrogen effect or bind to estrogen receptors.
(Non-Steroidal Estrogen, NCI Thesaurus)
The test looks at the activity of 21 different genes in breast cancer tissue of women who have early-stage breast cancer that is estrogen receptor positive and has not spread to the lymph nodes.
(Oncotype DX breast cancer assay, NCI Dictionary)
Oncotype DX is validated for use in breast cancer patients whose disease is newly diagnosed, stage I or II, node-negative, estrogen receptor-positive and who will be treated with tamoxifen.
(Oncotype DX breast cancer assay, NCI Thesaurus)
The hydrochloride salt of the partial estrogen antagonist nafoxidine.
(Nafoxidine Hydrochloride, NCI Thesaurus)
A triphenylethylene nonsteroidal agent that acts as a partial estrogen antagonist.
(Nafoxidine, NCI Thesaurus)
A main metabolite of the selective estrogen receptor modulator tamoxifen with anti-estrogen activity.
(N-Desmethyltamoxifen, NCI Thesaurus)
An anticancer drug that is used to decrease estrogen production and suppress the growth of tumors that need estrogen to grow.
(Anastrozole, NCI Dictionary)
Drug treatment to block the action of the female hormone estrogen.
(Antiestrogen Therapy, NCI Thesaurus)
