Library / English Dictionary

EXONUCLEASE

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A nuclease that releases one nucleotide at a time (serially) beginning at one of a nucleic acid

Classified under:

Nouns denoting substances

Hypernyms ("exonuclease" is a kind of...):

nuclease (general term for enzymes that catalyze the hydrolysis of nucleic acid by cleaving chains of nucleotides into smaller units)

Credits

 Context examples: 

This complex possesses manganese-dependent single-stranded DNA endonuclease and 3-prime to 5-prime exonuclease activities.

(MRE11/RAD50 Double-Strand Break Repair Complex, NCI Thesaurus/from OMIM)

The DNA found between nucleosomes on chromatin; since it is not complexed to proteins as strongly as other forms of DNA, it is accessible to exonuclease hydrolysis.

(Linker DNA, NCI Thesaurus)

Normally, during replication of the lagging-strand DNA template, an RNA primer is removed either by an RNase H or by the 5 to 3 exonuclease activity of DNA pol I, and the DNA ligase joins the Okazaki fragments.

(DNA Replication Pathway, NCI Thesaurus/KEGG)