| Health / Medical Topics |
Fadrozole Hydrochloride
The hydrochloride salt of the nonsteroidal aromatase inhibitor fadrozole with potential antineoplastic activity. Fadrozole specifically inhibits aromatase, blocking the aromatization of androstenedione and testosterone into estrone and estradiol, respectively, the final step in estrogen biosynthesis; the reduction in estrogen levels may inhibit growth in estrogen-dependent cancers. Aromatase, a member of the cytochrome P-450 superfamily, is found in many tissues; overexpression has been linked to the development of preneoplastic and neoplastic changes in breast tissue. (NCI Thesaurus)
YOU MAY ALSO LIKE
Human FADD wild-type allele is located in the vicinity of 11q13.3 and is approximately 4 kb in length. This allele, which encodes…
This gene is involved in signal transduction and the activation of caspase-dependent apoptosis.
The body of teachers and administrators at a school.
A type of clinical study in which two or more treatments are given alone and in combination, such that all possible combinations…
The determination of the amount of factor XIV present in a sample.
The determination of the amount of Factor XIV activity present in a sample.
