| Health / Medical Topics |
Fas-Associated Via Death Domain
Acts as an adaptor protein, interacting with FAS or TNFR-2. The death domain of these receptors binds to the corresponding domain of FADD, which in turn recruits the zymogen form of the death protease FLICE, activating a protease cascade which results in apoptosis. (NCI Thesaurus)
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Lymphoproliferative disease of spleen and nodes, no apoptosis, medium sized lymphocytes
