FCGR2B wt Allele

Human FCGR2B wild-type allele is located within 1q23 and is approximately 15 kb in length. This allele, which encodes low affinity immunoglobulin gamma Fc region receptor II-b protein, is involved in B-cell activation, host defense responses against foreign pathogens, and immune responses. Chromosomal translocation t(1;22)(q22;q11) leads to FCGR2B hyperexpression in a follicular lymphoma. (NCI Thesaurus)

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FCGR2B Gene

This gene plays a role in the inhibition of immune functions and cellular proliferation.

FCGR2A wt Allele

Human FCGR2A wild-type allele is located within 1q23 and is approximately 14 kb in length. This allele, which encodes low affinity immunoglobulin…

FCGR2A Gene

This gene is involved in the regulation of host immune responses and phagocytosis.

FCGR1A wt Allele

Human FCGR1A wild-type allele is located within 1q21.2-q21.3 and is approximately 10 kb in length. This allele, which encodes high affinity immunoglobulin…

FCGR1A Gene

This gene is involved in the immune response.

FCER2 wt Allele

Human FCER2 wild-type allele is located 19p13.3 and is approximately 13 kb in length. This allele, which encodes low affinity immunoglobulin epsilon…