| Library / English Dictionary |
GLUCOCORTICOID
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A steroid hormone that is produced by the adrenal cortex of animals; affects functioning of gonads and has anti-inflammatory activity
Classified under:
Hypernyms ("glucocorticoid" is a kind of...):
endocrine; hormone; internal secretion (the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect)
adrenal cortical steroid; corticoid; corticosteroid (a steroid hormone produced by the adrenal cortex or synthesized; administered as drugs they reduce swelling and decrease the body's immune response)
Hyponyms (each of the following is a kind of "glucocorticoid"):
corticosterone (secreted by the adrenal cortex; involved in regulating water and electrolyte balance in the body)
Pediapred; prednisolone; Prelone (a glucocorticoid (trade names Pediapred or Prelone) used to treat inflammatory conditions)
Deltasone; Liquid Pred; Meticorten; Orasone; prednisone (a dehydrogenated analogue of cortisol (trade names Orasone or Deltasone or Liquid Pred or Meticorten); used as an anti-inflammatory drug in the treatment of arthritis and as an immunosuppressant)
Context examples:
A pyridine derivative and a glucocorticoid synthesis inhibitor.
(Metyrapone, NCI Thesaurus)
A glucocorticoid receptor agonist with metabolic, anti-inflammatory, and immunosuppressive activity.
(Clocortolone Pivalate, NCI Thesaurus)
NF-kB is a transcription factor involved in signaling by inflammatory factors such as TNF, and is repressed by glucocorticoids.
(Corticosteroid Cardioprotection Pathway, NCI Thesaurus/BIOCARTA)
The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
(Beclomethasone Dipropionate, NCI Thesaurus)
Betamethasone valerate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression.
(Betamethasone Valerate, NCI Thesaurus)
A life threatening condition due to inadequate levels of glucocorticoids in an individual with adrenal insufficiency.
(Adrenal Crisis, NCI Thesaurus)
It is responsible for the synthesis of glucocorticoids, aldosterone, and androgens.
(Adrenal Cortical Cell, NCI Thesaurus)
It secretes mineralocorticoids, androgens, and glucocorticoids.
(Adrenal cortex, NLM, Medical Subject Headings)
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
(Beclomethasone, NCI Thesaurus)
Alclometasone dipropionate is a glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, immunosuppressive, antipruritic, and vasoconstrictive effects of natural glucocorticoids.
(Alclometasone Dipropionate, NCI Thesaurus)
