Granisetron hydrochloride

Pronunciation

Definition 1

A drug used to prevent nausea and vomiting caused by chemotherapy and radiation therapy. It is also used to prevent nausea and vomiting after surgery. Granisetron hydrochloride blocks the action of the chemical serotonin, which binds to certain nerves and may trigger nausea and vomiting. Blocking serotonin may help lessen nausea and vomiting. It is a type of serotonin receptor antagonist and a type of antiemetic. Also called Kytril. (NCI Dictionary)

Definition 2

The hydrochloride salt of an indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. (NCI Thesaurus)

Definition 3

A drug used to treat nausea and vomiting caused by cancer treatment. It is a type of serotonin receptor antagonist and a type of antiemetic. (NCI Dictionary)

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