GSTM1 wt Allele

Human GSTM1 wild-type allele is located in the vicinity of 1p13.3 and is approximately 6 kb in length. This allele, which encodes glutathione S-transferase Mu 1 protein, is involved in the conjugation of reduced glutathione with both endogenous and exogenous hydrophobic electrophilic compounds. Null mutations of the GSTM1 gene are associated with several types of human cancer such as lung, bladder, and head and neck cancers. (NCI Thesaurus)

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GSTM1 Gene

This gene plays a role in the phase II metabolism of both endogenous compounds and xenobiotics.

GSTA1 wt Allele

Human GSTA1 wild-type allele is located in the vicinity of 6p12.2 and is approximately 13 kb in length. This allele, which encodes…

GSTA1 Gene

This gene is involved in glutathione metabolism.

GSK3A wt Allele

Human GSK3A wild-type allele is located in the vicinity of 19q13.2 and is approximately 12 kb in length. This allele, which encodes…

GSK3A Gene

This gene is involved in carbohydrate metabolism, signal transduction and the regulation of apoptosis.

GSK1070916A

A substance being studied in the treatment of some types of cancer. It blocks certain enzymes (Aurora kinases) involved in cell division…