Health / Medical Topics |
GSTP1 wt Allele
Human GSTP1 wild-type allele is located within 11q13 and is approximately 3 kb in length. This allele, which encodes glutathione S-transferase Pi protein, plays a role in the conjugation of reduced glutathione with both endogenous and exogenous hydrophobic electrophilic compounds. Due to promoter hypermethylation, the GSTP1 gene is not expressed in prostatic intraepithelial neoplasia or prostatic adenocarcinomas. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene is involved in phase II metabolism of both endogenous compounds and xenobiotics.
Human GSTM4 wild-type allele is located in the vicinity of 1p13.3 and is approximately 9 kb in length. This allele, which encodes…
This gene plays a role in the metabolism of both glutathione and xenobiotics.
Human GSTM3 wild-type allele is located in the vicinity of 1p13.3 and is approximately 8 kb in length. This allele, which encodes…
This gene is involved in both glutathione metabolism and cellular detoxification.
Human GSTM1 wild-type allele is located in the vicinity of 1p13.3 and is approximately 6 kb in length. This allele, which encodes…